BET 1: LOPINAVIR-RITONAVIR AND COVID-19

A short-cut review of the literature was carried out to examine whether the use of lopinavir-ritonavir leads to improved outcomes in patients admitted to hospital with COVID-19. Five papers were identified as clinically useful using the reported search strategy. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of the best papers are tabulated. It is concluded that there is no current evidence to support the use of lopinavir-ritonavir in COVID-19 to improve clinical outcomes.